Friday, May 1, 2009

What is Zollinger-Ellison Syndrome

Zollinger-Ellison Syndrome is a disease where your stomach produces high amounts of hydrochloric acid in response to the enzyme gastrin of the stomach. It could be due to a tumor growth in your body, either in the stomach or the pancreas. The tumor secretes the enzyme gastrin at an uncontrolled rate.

The high acidity of the stomach results in peptic ulcer formation. It causes people pain and many times diarrhea. Vomiting blood, difficulty in eating and steatorrhea can also result because of this disease.

The tumor formation in stomach or pancreas could be a result of another condition known as Multiple Endocrine Neoplasia type I (MEN I). People with MEN I syndrome also suffer with other tumors at other locations in the body for example parathyroid glands or pituitary glands.

Usually proton pump blockers like Omeprazole or H2-receptor blockers like Ranitidine are given to lower the acidity of the stomach. The resection of tumors is performed and chemotherapy is conducted.